Newsletter Volume 40, Number 2, 2025

DMPK 61に掲載予定の論文一覧

[Editorial]

Editorial

Future direction of animal alternative/microphysiological systems in drug discovery and development

Hiroshi Arakawa, Kazuo Takayama

 

[Review]

Review article

Advanced in vitro evaluation of drug-induced kidney injury using microphysiological systems in drug discovery and development

Hiroshi Arakawa, Kohei Matsushita, Naoki Ishiguro

 

[Regular Articles]

Research article

In vitro characterization of taurine transport using the human brain microvascular endothelial cell line as a human blood-brain barrier model

Yuma Tega, Yusuke Kawauchi, Shin-ichi Akanuma, Mai Inagaki, … Ken-ichi Hosoya

 

Research article

Establishment of endogenous canine MUC1 knock-out MDCKII cells using CRISPR-Cas9 and evaluation of drug permeation

Hisanao Kishimoto, Kaori Miyazaki, Moeko Omori, Kei Higuchi, … Katsuhisa Inoue

 

Research article

Comprehensive in vitro evaluation of the inhibitory effects of relatively high molecular weight peptides on drug-drug interaction-associated four liver transporters and its association with physicochemical properties

Rika Ishikawa, Takashi Misawa, Yosuke Demizu, Yoshiro Saito, … Kosuke Saito

 

[Notes]

Short communication

Substrate inhibition potential of arachidonic acid on 14,15-epoxidation, a biological drug developmental target, mediated by recombinant human cytochrome P450 2J2 and 2C8 enzymes

Ayaka Kojima, Masayuki Nadai, Hiroshi Yamazaki, Miki Katoh


●各論文のabstractおよび論文内容詳細については、以下のリンクをご覧ください。
Drug Metabolism and Pharmacokinetics | Vol 61, April 2025 | ScienceDirect.com by Elsevier