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Program/Timetable
Distinguished Lecture
- Distinguished Lecture 1
Tuesday, November 20, 2012 14:10-15:10
Chair: Yuichi Sugiyama
Presenter:Marianne K. DeGorter
- Distinguished Lecture 2
Wednesday, November 21, 2012 13:45-14:45
Chair: Yasushi Yamazoe
Presenter: Masahiko Negishi
President's Lecture
Wednesday, November 21, 2012 14:45-15:10
Chair: Kan Chiba
Presenter: Hiroshi Suzuki
Symposium
- Symposium1
Approaches to Induction at Drug Discovery and Development
Tuesday, November 20, 2012 9:30-12:00
Organizers, Chairs:
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Masato Chiba |
Taiho Pharmaceutical Co., Ltd |
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Toshiyuki Kume |
Mitsubishi Tanabe Pharma Corporation |
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Takashi Hirota |
Tokyo University of Science |
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Toshiya Moriwaki |
Takeda Pharmaceutical Co., Ltd |
Presenters:
| S1-1 |
Induction mechanisms of drug-metabolizing enzymes |
Kaoru Kobayashi |
Laboratory of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Chiba University |
| S1-2 |
To Minimize Risk of DDI Caused by Induction of Drug Metabolizing Enzyme |
Akihiro Hisaka |
Pharmacology and Pharmacokinetics, The University of Tokyo Hospital, Japan |
| S1-3 |
CYP INDUCTION SCREENING USING CRYOPRESERVED HUMAN HEPATOCYTES IN DRUG DEVELOPMENT |
Kunihiro Ohta |
Chugai Pharmaceutical Co., Ltd. |
| S1-4 |
Investigation of drug-drug interaction caused by CYP3A4 induction using in vitro and in vivo models |
Maki Hasegawa |
Pharmacokinetic Research Laboratories, Research Division, Kyowa Hakko Kirin Co., Ltd. |
| S1-5 |
CYP1A INDUCTION AND CLINICAL RESULTS OF ANTIANGIOGENIC AGENT TSU-16 |
Kazuaki Matsuoka |
Pharmacokinetics Research Lab., Tokushima Research Center, Taiho Pharmaceutical Co., Ltd. |
- Symposium2
Physiological Roles of Transporters: Understanding their integrated functions
Tuesday, November 20, 2012 15:10-17:40
Organizers:
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Takashi Izumi |
Daiichi Sankyo Co.,Ltd. |
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Kousei Ito |
The University of Tokyo Hospital |
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Hiroyuki Kusuhara |
The University of Tokyo |
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Toshiharu Horie |
Chiba University |
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Yoshihisa Shitara |
Meiji Seika Pharma Co., Ltd. |
Chairs:
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Yukio Kato |
Kanazawa University |
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Toshiya Katsura |
Kyoto University Hospital |
Presenters:
| S2-1 |
Pleiotropy of membrane transporters - Uncover hidden function for better drug discovery and development - |
Ikumi Tamai |
Institute of Medical, Pharmaceutical and Health Sciences, Faculty of Pharmaceutical Sciences, Kanazawa University |
| S2-2 |
METABOLOMICS AND PROTEOMICS IN TRANSPORTER RESEARCH |
Yoshikatsu Kanai |
Division of Bio-system Pharmacology, Department of Pharmacology, Graduate School of Medicine, Osaka University |
| S2-3 |
Lifestyle-related diseases and transporters |
Tappei Takada |
Department of Pharmacy, The University of Tokyo Hospital, Faculty of Medicine, The University of Tokyo |
| S2-4 |
Molecular and functional identification of novel transporters |
Katsuhisa Inoue |
Graduate School of Pharmaceutical Sciences, Nagoya City University |
| S2-5 |
NEW DRUG DEVELOPMENT FOR LIVER DISORDERS WITH INTRAHEPATIC CHOLESTASIS |
Hisamitsu Hayashi |
Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo |
- Symposium3
Translational Medicine Promoted By Pharmacokineticists
Wednesday, November 21, 2012 9:20-11:50
Organizers:
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Shigeru Ohmori |
Shinshu University Hospital |
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Kousei Ito |
The University of Tokyo Hospital |
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Ariyoshi Noritaka |
Chiba University Hospital |
Chairs:
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Hideyuki Saito |
Kumamoto University |
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Tomohiro Terada |
Shiga University of Medical Science Hospital |
Presenters:
| S3-1 |
PK/PD APPROACHES FOR OPTIMAL MOLECULAR TARGETED CANCER THERAPY |
Tomohiro Terada |
Department of Pharmacy, Shiga University of Medical Science Hospital |
| S3-2 |
Analyses of development mechanisms of adverse reactions related to kinase inhibitors |
Masashi Honma |
Department of Pharmacy, The University of Tokyo Hospital |
| S3-3 |
PHARMACOKINETICS AND PHARMACODYNAMICS OF ANTIMICROBIAL DRUGS: FROM BASIC THEORY TO CLINICAL PRACTICE |
Kazuro Ikawa |
Department of Clinical Pharmacotherapy, Hiroshima University |
| S3-4 |
Contribution of Pharmacokinetics Study to the Global Clinical Trials |
Masahiro Tohkin |
Graduate School of Pharmaceutical Sciences, Nagoya City University |
| S3-5 |
APPROACH OF TRANSLATINAL MEDICINE IN NEW DRUG DEVELOPMENT |
Shinji Tatami |
Clinical PK/PD, Medical Development Div., Nippon Boehringer Ingelheim Co., Ltd. |
- Symposium4
Recent Advances in Drug Metabolism-related Toxicology
Wednesday, November 21, 2012 9:20-11:50
Organizer, Chairs:
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Masakiyo Hosokawa |
Chiba Institute of Science |
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Yoshiro Saito |
National Institute of Health Sciences |
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Hiroshi Yamazaki |
Showa Pharmaceutical University |
Chair:
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Shigeru Ohta |
Hiroshima University |
Presenters:
| S4-1 |
Considerations for therapeutic protein-drug interactions (TP-DIs) |
Yoshiro Saito |
National Institute of Health Sciences |
| S4-2 |
HUMAN DRUG METABOLITES BIOACTIVATED BY CYTOCHROME P450 ENZYMES |
Hiroshi Yamazaki |
Showa Pharmaceutical University |
| S4-3 |
Acetaminophen hepatotoxicity: A model to study mechanisms of idiosyncratic drug-induced liver injury |
Yasuhiro Masubuchi |
Laboratory of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Chiba Institute of Science |
| S4-4 |
Adverse drug reactions caused by P450 and non-450 enzymes: methemoglobinemia and liver injury |
Miki Nakajima |
Faculty of Pharmaceutical Sciences, Kanazawa University |
Forum 2012
- Forum 2012
Current and Future Development of Therapeutic Oligonucleotides
Thursday, November 22, 2012 14:00-17:00
Organizers, Chairs:
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Eriko Uchida |
National Institute of Health Sciences |
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Hideyoshi Harashima |
Hokkaido University |
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Ryosei Kawai |
Daiichi Sankyo Co.,Ltd. |
Presenters:
| F-1 |
Trends and issues in the development of therapeutic oligonucleotides |
Eriko Uchida |
Cellular and Gene Therapy Products, National Institute of Health Sciences |
| F-2 |
Case studies of research and development of oligonucleotide medicine and medical device |
Takahiro Nakazawa |
Research and Development Division, AnGes MG, Inc. |
| F-3 |
Bioanalysis of nucleic acid medicines in drug metabolism and pharmacokinetics research |
Hisao Shimizu |
Drug Metabolism and Pharmacokinetics Research Laboratories, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited |
| F-4 |
MULTIFUNCTIONAL ENVELOPE-TYPE NANO DEVICE FOR NANO MEDICINE |
Hideyoshi Harashima |
Faculty of Pharmaceutical Sciences, Hokkaido University |
| F-5 |
The future direction of regulation for nucleic acid medicine |
Teruyo Arato |
Graduate School of Medicine , Hokkaido University |
Round Table Discussion
- Round Table1
Discussion on decision making easy to approach from candidate selection to clinical development
Thursday, November 22, 2012 14:00-17:00
Organizers, Chairs:
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Toru Horie |
D-Three Institute |
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Yusuke Tanigawara |
Keio University |
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Fumiyoshi Yamashita |
Kyoto University |
Presenters:
| R1-1 |
In silico strategy for ADMET prediction and profiling in drug discovery phase |
Masateru Ohta |
Medicinal Chemistry Dept., Chugai Pharmaceutical co. ltd. |
| R1-2 |
Importance of the Structure-metabolism Relationship Study for the Drug Candidate Selection |
Yukio Tada |
Open Innovation Center for Drug Discovery, The University of Tokyo |
| R1-3 |
Move ahead on effective early clinical development |
Takeshi Tahara |
Department of Clinical Development I (Oncology), Taiho Pharmaceutical Co., Ltd. |
| R1-4 |
The prediction of safety in human from non-clinical data |
Yuji Kumagai |
Kitasatato Clinical Research Center, Kitasato University, Scool of Medicine |
| R1-5 |
New systems model for translational medicine |
Kazuhiro Sakurada |
Sony Computer Science Laboratories, Inc. |
- Round Table2
International Transporter Consortium Workshop 2: White Paper Preparation and Discussion for Future Activities of ITC
Thursday, November 22, 2012 14:00-17:00
Organizer, Chair:
Presenters:
| R2-1 |
Transporter-mediated drug interaction studies on new drug applications: Current situations and regulatory views in Japan |
Daisuke Iwata |
Office of New Drug IV, Pharmaceuticals and Medical Devices Agency (PMDA) |
| R2-2 |
INTERNATIONAL TRANSPORTER CONSORTIUM (ITC): FUTURE DIRECTIONS OF PHARAMCOGENOMICS AND IN-SILICO QSAR ANALYSIS ON HUMAN DRUG TRANSPORTERS |
Toshihisa Ishikawa |
Omics Science Center, RIKEN Yokohama Institute |
| R2-3 |
Transporter Biology: A New Frontier in Drug Discovery and Development |
Yong Huang |
OPTIVIA President & CEO |
| R2-4 |
JSSX ROUNFTABLE ON TRANSPORTERS |
Shiew-Mei Huang |
FDA CDER Deputy Director, USA |
Open Symposium
- Open Symposium1
Advance in the study of drug metabolism and disposition in 2012-1
Thursday, November 22, 2012 9:20-11:40
Chairs:
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Ikumi Tamai |
Kanazawa University |
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Hiroyuki Kusuhara |
The University of Tokyo |
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Hideyuki Yamada |
Kyushu University |
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Tsuyoshi Yokoi |
Kanazawa University |
- Open Symposium2
Advance in the study of drug metabolism and disposition in 2012-2
Thursday, November 22, 2012 9:20-11:40
Chairs:
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Shizuo Narimatsu |
Okayama University |
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Ichiro Ieiri |
Kyushu University |
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Mikihisa Takano |
Hiroshima University |
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Shinji Yamashita |
Setsunan University |
Oral Presentations
Poster Presentations
Luncheon Seminar
Exhibision
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