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DMPK Editors’ Award for the Most Excellent Article in 2022
- 【1st place】
Yasuto Kido*, Isamu Nanchi, Yasuyuki Fusamae, Takanobu Matsuzaki, Takanori Akazawa, Hiromi Sawada, Makoto Iwasaki, Kimiko Nishida, Eiichi Tsuchiya, Tomohiko Okuda
Species difference in brain penetration of P-gp and BCRP substrates among monkey, dog and mouse.
Volume 42, 100426, February 2022.
https://doi.org/10.1016/j.dmpk.2021.100426
- 【2nd place】
Takayoshi Nakaoka, Ken-ichi Kaneko, Satsuki Irie, Aya Mawatari, Ami Igesaka, Yuta Uetake, Hidenori Ochiai, Takashi Niwa, Emi Yamano, Yasuhiro Wada, Masaaki Tanaka, Kohei Kotani, Hideki Kawahata, Joji Kawabe, Yukio Miki, Hisashi Doi, Takamitsu Hosoya, Maeda Kazuya, Hiroyuki Kusuhara, Yuichi Sugiyama, Yasuyoshi Watanabe*
Clinical evaluation of [18F]pitavastatin for quantitative analysis of hepatobiliary transporter activity.
Volume 44, 100449, June 2022.
https://doi.org/10.1016/j.dmpk.2022.100449
- 【3rd place】
Shotaro Uehara, Yuichiro Higuchi, Nao Yoneda, Kenji Kawai, Masafumi Yamamoto, Hidetaka Kamimura, Yuichi Iida, Mitsuo Oshimura, Yasuhiro Kazuki, Hiroshi Yamazaki, Hayato Hikita, Tetsuo Takehara, Hiroshi Suemizu*
An improved TK-NOG mouse as a novel platform for humanized liver that overcomes limitations in both male and female animals.
Volume 42, 100410, February 2022.
https://doi.org/10.1016/j.dmpk.2021.100410
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DMPK Editors' Award for the Most Excellent Article in 2021
- 【1st Place】
Yukihiro Shibata, Yuta Tamemoto, Sheelendra Pratap Singh, Aoi Yoshitomo, Shizuka Hozuki, Hiromi Sato, Akihiro Hisaka*
Plausible drug interaction between cyclophosphamide and voriconazole via inhibition of CYP2B6.
Volume 39, 100396, August 2021.
https://doi.org/10.1016/j.dmpk.2021.100396
- 【2nd Place】
Katsunori Sasahara*, Masakazu Shibata, Hiroyuki Sasabe, Tomoki Suzuki, Kenji Takeuchi, Ken Umehara, Eiji Kashiyama
Predicting drug metabolism and pharmacokinetics features of in-house compounds by a hybrid machinelearning model.
Volume 39, 100395, August 2021.
https://doi.org/10.1016/j.dmpk.2021.100395
- 【3rd Place】
Chikako Shibazaki, Tomoyuki Ohe, Kyoko Takahashi, Shigeo Nakamura, Tadahiko Mashino*
Development of fluorescent-labeled trapping reagents based on cysteine to detect soft and hard electrophilic reactive metabolites.
Volume 39, 100386, August 2021.
https://doi.org/10.1016/j.dmpk.2021.100386
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DMPK Editors' Award for the Most Excellent Article in 2020
- 【1st Place】
6-Hydroxyindole is an endogenous long-lasting OATP1B1 inhibitor elevated in renal failure patients
Yusuke Masuo, Ken-ichi Fujita, Kenji Mishiro, Natsumi Seba, Tatsuya Kogi, Hidenori Okumura, Natsumi Matsumoto, Munetaka Kunishima, Yukio Kato
Volume 35, Issue 6, Pages 555-562
https://doi.org/10.1016/j.dmpk.2020.09.001
- 【2nd Place】
Pharmacokinetic functions of human induced pluripotent stem cell-derived small intestinal epithelial cells
Tomoki Kabeya, Shinji Mima, Yuki Imakura, Toshihide Miyashita, Izumi Ogura, Tadanori Yamada, Tomoya Yasujima, Hiroaki Yuasa, Takahiro Iwao, Tamihide Matsunaga
Volume 35, Issue 4, Pages 374-382
https://doi.org/10.1016/j.dmpk.2020.04.334
- 【3rd Place】
Quantitative application of flow cytometry for the analysis of circulating human T cells: A preclinical pharmacokinetic study
Syunsuke Yamamoto, Shin-Ichi Matsumoto, Hisao Shimizu, Hideki Hirabayashi
Volume 35, Issue 2, Pages 207-213
https://doi.org/10.1016/j.dmpk.2019.11.003
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DMPK Editors' Award for the Most Excellent Article in 2019
- 【1st Place】
Effect of OATP1B1 genotypes on plasma concentrations of endogenous OATP1B1 substrates and drugs, and their association in healthy volunteers
Daiki Mori, Yushi Kashihara, Takashi Yoshikado, Miyuki Kimura, Takeshi Hirota, Shunji Matsuki, Kazuya Maeda, Shin Irie, Ichiro Ieiri, Yuichi Sugiyama, Hiroyuki Kusuhara
Volume 34, Issue 1, Pages 78-86
https://doi.org/10.1016/j.dmpk.2018.09.003
- 【2nd Place】
Quantitative investigation of hepatobiliary transport of [11C]telmisartan in humans by PET imaging
Kazuya Maeda, Akihito Ohnishi, Masahiro Sasaki, Yasuhiko Ikari, Kazuki Aita, Yasuyoshi Watanabe, Hiroyuki Kusuhara, Yuichi Sugiyama, Michio Senda
Volume 34, Issue 5, Pages 293-299
https://doi.org/10.1016/j.dmpk.2019.02.004
- 【3rd Place】
Investigation of non-linear Mate1-mediated efflux of trimethoprim in the mouse kidney as the mechanism underlying drug-drug interactions between trimethoprim and organic cations in the kidney
Tomoko Kito, Sumito Ito, Tadahaya Mizuno, Kazuya Maeda, Hiroyuki Kusuhara
Volume 34, Issue 1, Pages 87-94
https://doi.org/10.1016/j.dmpk.2018.08.005
- 【3rd Place】
Microdosing clinical study to clarify pharmacokinetic and pharmacogenetic characteristics of atorvastatin in Japanese hypercholesterolemic patients
Nora Lee, Kazuya Maeda, Shinya Fukizawa, Ichiro Ieiri, Atsuko Tomaru, Hironobu Akao, Kenji Takeda, Mizuho Iwadare, Osamu Niwa, Tougen Masauji, Naoe Yamane, Kouji Kajinami, Hiroyuki Kusuhara, Yuichi Sugiyama
Volume 34, Issue 6, Pages 387-395
https://doi.org/10.1016/j.dmpk.2019.08.004
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DMPK Editors' Award for the Most Excellent Article in 2018
- 【1st Place】
Quantitative analysis of elevation of serum creatinine via renal transporter inhibition by trimethoprim in healthy subjects using physiologically-based pharmacokinetic model
Tomohisa Nakada, Toshiyuki Kudo, Toshiyuki Kume, Hiroyuki Kusuhara, Kiyomi Ito
Volume 33, Issue 1, Pages 103-110, 2018
https://doi.org/10.1016/j.dmpk.2017.11.314
- 【2nd Place】
miR-141-3p commonly regulates human UGT1A isoforms via different mechanisms
Naoyuki Tatsumi, Shinsaku Tokumitsu, Masataka Nakano, Tatsuki Fukami, Miki Nakaj
ima Volume 33, Issue 4, Pages 203-210, 2018
https://doi.org/10.1016/j.dmpk.2018.05.002
- 【3rd Place】
Physiological based pharmacokinetic modeling to estimate in vivo Ki of ketoconazole on renal P-gp using human drug-drug interaction study result of fesoterodine and ketoconazole
Masayo Oishi, Yuma Takano, Yutaka Torita, Bimal Malhotra, Koji Chiba
Volume 33, Issue 1, Pages 90-95, 2018
https://doi.org/10.1016/j.dmpk.2017.11.005
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DMPK Editors' Award for the Most Excellent Article in 2015
- 【1st Place】
CYP1A1 and CYP1A2 expression levels are differentially regulated in three-dimensional spheroids of liver cancer cells compared to two-dimensional monolayer cultures
Jun Terashima, Shinpei Goto, Hiroki Hattori, Sawaka Hoshi, Midori Ushirokawa, Kenzo Kudo,Wataru Habano, Shogo Ozawa
Vol. 30 (2015) No. 6 p. 434-440
http://www.sciencedirect.com/science/article/pii/S1347436715000592
- 【2nd Place】
Dehydroepiandrosterone sulfate, a useful endogenous probe for evaluation of drug?drug interaction on hepatic organic anion transporting polypeptide (OATP) in cynomolgus monkeys
Masaki Watanabe, Takao Watanabe, Masashi Yabuki, Ikumi Tamai
Vol. 30 (2015) No. 2 p. 198-204
http://www.sciencedirect.com/science/article/pii/S1347436714000305
- 【3rd Place】
Modeling approach for multiple transporters-mediated drug?drug interactions in sandwich-cultured human hepatocytes: Effect of cyclosporin A on hepatic disposition of mycophenolic acid phenyl-glucuronide
Norikazu Matsunaga, Kaori Suzuki, Takeo Nakanishi, Mikio Ogawa, Haruo Imawaka, Ikumi Tamai
Vol. 30 (2015) No. 2 p. 142-148
http://www.sciencedirect.com/science/article/pii/S1347436714000159
... Go DMPK (Vo.17, 2002〜current issue)
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